Best-Rest Formula supports healthy sleep cycles by encouraging an easy transition to sleep and a restful night’s sleep.This unique blend contains the time-tested support of valerian, passionflower, chamomile, lemon balm and hops, which act to calm and relax the central nervous system.Melatonin also facilitates the onset of sleep and sleep efficiency. GABA and l-theanine are included for their ability to promote alpha wave production in the brain, an indication of relaxation.Pyridoxal-5-phosphate, melatonin and GABA (gammaaminobutyric acid) are synthetic. Theanine is derived from fermentation. Deodorized valerian extract is derived from Valeriana officinalis root and standardized to contain 0.8% valernic acids. Lemon balm extract is derived from Melissa officinalis leaf and standardized to contain 5% rosemarinic acid. Hops is derived from Humulus lupulus L. aerial parts and standardized to contain 2.9% flavonoids. Passion flower extract is derived from Passiflora incarnata L. aerial parts and standardized to contain 3.5% vitexin. Chamomile extract is derived from Matricaria recutita flowers. Maltodextrin is derived from potato. Gum arabic is derived from acacia tree. Ascorbyl palmitate is derived from corn dextrose fermentation and palm oil. Hypoallergenic plant fiber is derived from pine cellulose.SUGGESTED USAGEPure Encapsulations recommends 1–2 capsules 30–60 minutes before bedtime.INGREDIENTSTwo vegetable capsules contain:pyridoxal 5' phosphate (activated B6)5 mg.melatonin1 mg.GABA (gamma-aminobutyric acid)300 mg.l-theanine50 mg.valerian (valeriana officinalis) extract (root)400 mg.(deodorized)(standardized to contain 0.8% valerenic acids)lemon balm (melissa officinalis) extract (leaf)150 mg.(standardized to contain 5% rosemarinic acid)hops (humulus lupulus l.) extract (aerial parts)150 mg.passion flower (passiflora incarnata l.) extract100 mg.(aerial parts)(standardized to contain 3.5% vitexin)chamomile (matricaria recutita) extract (flower)100 mg.ascorbyl palmitate (fat-soluble vitamin C)40 mgOther ingredients: ascorbyl palmitate, maltodextrin, hypoallergenic plant fiber (cellulose), gum arabic, silica, vegetarian capsule (cellulose, water)WARNINGSNot to be taken by pregnant or lactating women. Best-Rest Formula may have sedating effects and is for bedtime use only. Melatonin may be contra-indicated in depression, seasonal affective disorder, schizophrenia, autoimmune disease or asthma. Valerian has been associated with vivid dreams and GI upset. Chamomile is not recommended for individuals with sensitivity to botanicals from the Asteraceae/Compositae family. In rare cases, passionflower can cause headache, dizziness, joint pain or ataxia. There is one case report of ventricular tachycardia following passionflower administration. Consult your physician for more information.Melatonin is contra-indicated with MAO inhibitors and corticosteroids. Chamomile may be contra-indicated with blood thinning medications. Best-Rest Formula is contra-indicated with other sedative medications, including benzodiazepines and CNS depressants. Consult your physician for more information.